BONE- Bio-fabrication of Orthopaedics in a New Era


Project Summary

A distinctive problem for NWE is the high occurrence of osteoporosis, leading to the highest rates of bone fractures of all EU regions. The number of hip replacements per 100k population is 214 in the NWE region versus the EU28 average of 153 (OECD 2016). The economic and societal burden of bone fractures is enormous and could be reduced by the implementation of affordable, curative healthcare solutions that ensure a faster recovery with lower health care costs. The emerging field of regenerative medicine offers potential solutions: smart implants, such as 3D scaffolds created through an innovative technology called electrospinning (ESP) hold the promise to support the regeneration of skeletal bone and replace the need for tissue donors, repeat operations or ongoing medication. However only local ESP technology R&D driven initiatives currently exist in NWE. The objective of BONE is therefore to accelerate the valorisation of cost-effective 3D smart implants fabricated by electrospinning technology (reaching TRL8) by collaboration between 4 research institutes, 4 business support organisations and 5 industry organisations. As such, BONE enables new jobs (15) to be created, two new products to be developed and tested in real life conditions (ESP technology and 3D smart implants) and intensive collaboration between Innovation leaders (Westphalia, London, Paris) strong innovators (Vlaams-Brabant, Southern-Limburg, Ireland) and moderate innovators (Nord-pas-de-Calais) in order to increase the regions’ innovation capacity in the area of regenerative medicine based on ESP technology.

Project Partners

Lead partner

Organisation Address Email Website
Maastricht Universiteit 40 Universiteitsingel
MAASTRICHT
6229 ER
Netherlands
l.moroni@maastrichtuniversity.nl merln.maastrichtuniversity.nl
Name Contact Name Email Country
Fraunhofer Institut für Lasertechnik Nadine Nottrodt nadine.nottrodt@ilt.fraunhofer.de Germany
The Electrospinning Company Limited Rob McKean brendan.robb@electrospinning.co.uk United Kingdom
Spraybase Ellen Byrne ebyrne@spraybase.com Ireland
Fianium Ltd Peter Moselund roger.kirke@fianium.com United Kingdom
Katholieke Universiteit Leuven, vertegenwoordigd door KU Leuven Research & Development Frank Luyten frank.luyten@uzleuven.be Belgium
Université de Lille Nicolas Blanchemain nicolas.blanchemain@univ-lille2.fr France
Medicen Paris Region Olivier Fontaine ofontaine@medicen.org France

News


BONE lunch symposium during the European Conference on Biomaterials (ESB) in Maastricht

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On the 10th of September 2018 the Interreg BONE consortium will organize a BONE lunch symposium during the European Conference on Biomaterials (ESB) in Maastricht. During this symposium invited speaker Prof. Dr. Juergen Groll (Wurzburg University) will present his work on the use of Biomaterials in the melt ESP Technology. Also the BONE project subsidized by Interreg NWE will be presented. Read More

BONE consortium meetings

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The BONE partners organized in October 2017 and January 2018 two BONE consortium meetings. The first one took place on the 5th and 6th of October 2017 in Maynooth, Dublin at the Spraybase facilities. The second one took place at the facilities of KUL on the 25th and 26th of January 2018. Both meetings were nice opportunities to visit the research facilities on site and to update each other in depth about the status of the different work packages. Read More

Kick-off BONE at Paris

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The official kick-off meeting of this international research project BONE, was held on Thursday July 6th in Paris, France at Medicen Paris Region. In addition, on Friday 7th of July, the first kick-off conference of BONE took place in conjunction with the Regenerative Medicine Europe matchmaking event organized by Medicen. This is an important event for BONE, as many of the stakeholders important to BONE are attending, spanning from academia, to industrial, regulatory body, and regional cluster actors. Read More


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